IIT Mandi

Researchers reveal how excess sugar causes fatty liver

New Delhi: In a new study conducted by the researchers at Indian Institute of Technology (IIT), Mandi has conclusively shown that excessive sugar intake leads to a fatty liver. This could offer an incentive for reducing sugar intake to stop non-alcoholic fatty liver disease (NAFLD) in its early stages. The unravelling of the molecular link between sugar and fat accumulation in liver is key to developing therapeutics for the disease, researchers said. A team of researchers from IIT Mandi, led by Dr Prosenjit Mondal, Associate Professor, School of Basic Sciences, has used complementary experimental approaches to establish the underlying biochemical…
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Researchers reveal key protein structure in COVID-19 virus

New Delhi: A team of researchers from the Indian Institute of Technology Mandi (IIT Mandi), led by Dr. Rajanish Giri, Assistant Professor, School of Basic Sciences, have elucidated the part of structure of a key protein in the COVID-19 virus, which helps in understanding its mode of action, its role in the spread and severity of the disease and development of antiviral therapeutics.  Current COVID-19 treatments simply manage symptoms while the body fights off the infection with its immune defence system. There are, as yet, no confirmed antiviral drugs that can stop the virus from replicating. One route to neutralising…
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New method for efficient removal of heavy metals from water

New Delhi : Heavy metals in water could lead to several neurological diseases in humans including Alzheimer's, Parkinson’s and multiple sclerosis. A research team at the Indian Institute of Technology (IIT) Mandi has developed a fibrous membrane filter using a biopolymer-based material that helps to separate out the heavy metals from water samples. These membranes contain adsorbents – materials that attract and hold the metals. “We tested with a prototype with four litres of heavy metal-laden water in the laboratory and have seen impressive results,” the scientists said. The researchers tested their membrane with copper laden water, to establish proof…
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Researchers devise new method to arm electronic gadgets against power fluctuations 

Researchers devise new method to arm electronic gadgets against power fluctuations 

New Delhi (India Science Wire): Indian researchers have developed the performance analysis of miniaturized circuitry used in modern devices such as mobile phones and tablets so that the devices may be designed for better performance even under erratic DC power supply. “There is a need to understand the design equations that take into account the miniaturized parts of mixed electronic circuitry in order to improve the performance of the device and enhance the robustness of the components to power fluctuations”, says, Dr. Hitesh Shrimali, Associate Professor, School of Computing & Electrical Engineering, IIT Mandi. His research team analyses the losses that occur…
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Opioid addiction treating drug may be repurposed for type 2 diabetes

Opioid addiction treating drug may be repurposed for type 2 diabetes

New Delhi: India is the diabetic capital of the world as every sixth person with diabetes in the world is an Indian. Insulin resistance has been a big challenge for researchers who seek to understand and treat it. Researchers from the Indian Institute of Technology, Mandi (IIT Mandi) have unraveled the mechanism by which insulin overload in the body causes insulin resistance that is associated with diabetes. They have found the drug that is used in treating opioid addiction can potentially reverse this phenomenon. “We’ve known that one of the causes of insulin resistance is inflammation”, says Dr Prosenjit Mondal,…
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